Home Pathophysiology Typhoid Fever Pathophysiology & Schematic Diagram

Typhoid Fever Pathophysiology & Schematic Diagram


Typhoid fever is termed as an acute illness accompanied by fever caused by a gram negative bacilli called as Salmonella typhi. It is transmitted via fecal- oral route through contaminated water supply or food. Clients who had harboured this infection may become asymptomatic for a long time and could be called as “carrier”. Those carriers can then be a cause for future outbreaks of typhoid fever especially if there is improper sanitation and handling of food and poor hygiene.

Incubation period from ingestion to presence of fever is between 2- 3 weeks or 3-60 days; this stage is simply asymptomatic until bacteremia occurs.

Clinical Manifestations of Typhoid Fever

a. Gradual Onset

  • Headache, malaise, poor appetite
  • Chills and fever
  • Rose spots- skin eruptions seen on abdomen, chest, back (within 3-4 days)
  • Splenomegaly in some cases

b. Second week

c. Gradual decline in fever and symptoms subsides, too.

Typhoid Fever Pathophysiology and Schematic Diagram

A dedicated registered nurse who loves to view life as a revolving conundrum with spectacles of light and an aspiring writer who wants to share her expertise and experience in the nursing profession. She had pursued continuing education specializing in Psychiatric Nursing but had her practice on MNCHN.