Originally posted 2014-11-26 11:50:28. Republished by Blog Post Promoter Systemic lupus erythematosus (SLE) is a type of autoimmune disease where the body’s own immune system attacks the healthy tissues by mistake. Lupus means ‘wolflike’ describing the distinctive rash over the cheeks and bridge of the nose appearing in most patients. Pathophysiology: The exaggerated autoantibody production...